Endocrine Abstracts

Regular exercise training has widespread health benefits by positively affecting nearly all organ systems of the body. Human physiology and the adaptive response to acute and chronic exercise training have largely been elucidated in the field of exercise science. This field has used model systems, organisms and has a strong history of human studies. Recently, the effect of exercising at different times of day and the interaction of exercise with circadian rhythm has been of gr...

Minerals and micronutrients deficiency have been reported to impair reproductive function. We investigated the influence of low salt diet and high salt diet on implantation and pregnancy in Sprague-Dawley rats. One hundred and forty-four rats were acclimatized and divided into three groups consisting of control/normal salt diet (0.3% salt), low salt diet (0.14% salt) and high salt diet (8% salt). All the rats were fed with respective diets for 6 weeks. The oestrous cycle was t...

Low birth weight has been reported in the offspring of rats fed with low salt diet. This study estimated the levels of maternal growth factors of pregnant rats fed with low salt and high salt diet. Seventy-two female Sprague–Dawley rats were acclimatized and divided into three groups consisting of control/normal salt diet (0.3% salt), low salt diet (0.14% salt) and high salt diet (8% salt). Rats were fed for six weeks and the cycles of the rats were observed in the 6th we...

Background: Pineal germ cell tumors are rare in adulthood. It usually comes to medical attention due to mass effect. Endocrine manifestations are also prominent in the clinical presentation and may precede neurologic symptoms.Clinical case: We report the case of a 30-year old male who presented with a 6-month history of bitemporal headache, doubling of vision and nonprojectile vomiting. Recall revealed that he exhibited symptoms of panhypopituitarism as ...

A 49 year-old Filipino male presented at the emergency room because of progressive dyspnea. He was diagnosed with papillary thyroid carcinoma by fine needle aspiration biopsy of his 7×5 cm thyroid mass 3 months prior to his current consultation. He was scheduled to undergo total thyroidectomy but he opted to postpone his surgery due to intermittent cough. On admission, a pulmonary mass with pleural effusion on the right was noted on chest radiograph. He was considered to ...

Introduction/objective: Elderly patients have a higher prevalence of hypernatremia. Previous studies suggested that impaired ADH secretion contributes to development of hypernatremia in the elderly. Copeptin is the C terminal part of the ADH precursor and is more stable in plasma than ADH. The aim of this study was to detect demographic and clinical characteristics of the elderly hypernatremic patient hospitalized in the internal medicine ward, and to increase the understandin...

Case 1: A 43-year-old man presented with two day history of sudden onset of headache and vomiting associated with diplopia and declining vision in the left eye for a few months. On admission he had a high grade fever. Neurological examination was unremarkable except for left sided blindness and blurred vision in right eye.Initial investigations revealed CRP of 181. CT head reported no haemorrhage or infarct. CSF analysis: WCC 24 (polymorphs 60% lymphocyt...

SARS-CoV-2 vaccination campaigns document a satisfactory high profile of protection against Covid-19 infection, but auto-immune/inflammatory diseases have been reported following Covid-19 vaccines. A 65-year-old woman reported two days following her first dose of the BNT162b2 mRNA vaccine tearing, eye irritation, conjunctival redness, peri-orbital swelling, spontaneous hematoma of the right lower eyelid, right greater than left proptosis, with a spontaneous improvement of symp...

Background: Primary hyperaldosteronism (PH) is a syndrome caused by excess aldosterone secretion, which leads to hypertension and hypokalemia and increased risk for target organ damage. The overproduction of aldosterone at the adrenal gland can be unilateral or bilateral. For unilateral disease the best treatment is unilateral adrenalectomy. According to international guidelines, most of the patients should have adrenal venous sampling (AVS) to distinguish between bilateral an...

Background: Thyroid dysfunction is associated with increased cardiovascular morbidity and mortality. Early detection may influence the clinical management of the patients. There is insufficient data about the prevalence and clinical significance of thyroid dysfunction in cardiovascular hospitalized patients.Aims: To study the prevalence of thyroid dysfunction in cardiovascular hospitalized patients, to characterize patients with high prevalence of thyroi...